Owner Vertex Pharmaceuticals Incorporated

Inventors Ruah, Sara Hadida; Hamilton, Matthew; Miller, Mark; Grootenhuis, Peter D. J.; Bear, Brian; McCarthy, Jason; Zhou, Jinglan

Agent Cullens

Pub. Number AU-B-2012201325

Parent 2006311650

Filing date 5 March 2012

Wipo publication date 29 March 2012

Acceptance publication date 3 May 2012

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

A61K 31/4418 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61K 31/5585 (2006.01)

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom