Owner Amgen Inc.

Inventors Bode, Christiane; Boezio, Alessandro; Cheng, Alan C.; Choquette, Deborah; Coats, James R.; Copeland, Katrina W.; Huang, Hongbing; La, Daniel; Lewis, Richard; Liao, Hongyu; Potashman, Michele; Stellwagen, John; Yi, Shuyan; Norman, Mark; Stec, Markian; Peterson, Emily A.; Graceffa, Russell

Agent Shelston IP

Pub. Number AU-A-2010249040

PCT Pub. Number WO2010/132598

Priority 61/177,825 13.05.09 US

Filing date 12 May 2010

Wipo publication date 18 November 2010

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/437 (2006.01)

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/52 (2006.01)

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or