Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates

Details for Australian Patent Application No. 2010212291 (hide)

Owner ImmunoGen, Inc.

Inventors Steeves, Rita; Lutz, Robert; Chari, Ravi; Xie, Hongsheng; Kovtun, Yelena; Widdison, Wayne

Agent Griffith Hack

Pub. Number AU-B-2010212291

Parent 2004282491

Filing date 12 August 2010

Wipo publication date 2 September 2010

Acceptance publication date 24 May 2012

International Classifications

C07D 491/12 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 (2006.01) Antineoplastic agents

Event Publications

2 September 2010 Application Open to Public Inspection

  Published as AU-B-2010212291

2 September 2010 Complete Application Filed

24 May 2012 Application Accepted

  Published as AU-B-2010212291

9 August 2012 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 16 Jul 2012 . Address for service in Australia - Griffith Hack GPO Box 3125 Brisbane QLD 4001 2011

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