Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates

Details for Australian Patent Application No. 2004282491 (hide)

Owner ImmunoGen, Inc.

Inventors Xie, Hongsheng; Lutz, Robert; Chari, Ravi; Kovtun, Yelena; Steeves, Rita

Agent Griffith Hack

Pub. Number AU-B-2004282491

PCT Pub. Number WO2005/037992

Priority 10/960,602 08.10.04 US; 60/509,901 10.10.03 US

Parent 2004247015

Filing date 12 October 2004

Wipo publication date 28 April 2005

Acceptance publication date 23 December 2010

International Classifications

C07D 491/12 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 (2006.01) Antineoplastic agents

Event Publications

16 March 2006 PCT application entered the National Phase

  PCT publication WO2005/037992 Priority application(s): WO2005/037992

19 June 2008 Alteration of Name

  The name of the applicant has been altered to ImmunoGen, Inc. 2005

23 December 2010 Application Accepted

  Published as AU-B-2004282491

3 March 2011 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 08 Feb 2011. Address for service in Australia - Griffith Hack Level 10 167 Eagle Street Brisbane QLD 4001 2005

30 June 2011 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 08 Feb 2011 2005

30 June 2011 Standard Patent Sealed

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