Antibody variants with higher binding affinity compared to parent antibodies

Details for Australian Patent Application No. 2008203527 (hide)

Owner Genentech, Inc.

Inventors Chen, Yvonne M; Lowman, Henry B; Muller, Yves

Agent Griffith Hack

Pub. Number AU-A-2008203527

Parent 2004216585

Filing date 6 August 2008

Wipo publication date 28 August 2008

International Classifications

C12N 15/13 (2006.01) Mutation or genetic engineering - Immunoglobulins

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/63 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using vectors

Event Publications

21 August 2008 Complete Application Filed

28 August 2008 Application Open to Public Inspection

  Published as AU-A-2008203527

18 November 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  Application withdrawn under section 141(1). Examination has been requested or an examination report has issued for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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