Antibody variants with higher binding affinity compared to parent antibodies

Details for Australian Patent Application No. 2004216585 (hide)

Owner Genentech, Inc.

Inventors Muller, Yves; Lowman, Henry B; Chen, Yvonne M

Agent Griffith Hack

Pub. Number AU-A-2004216585

Parent 17288

Filing date 28 September 2004

Wipo publication date 21 October 2004

International Classifications

C12N 015/13 Mutation or genetic engineering - Immunoglobulins

C12N 015/63 Mutation or genetic engineering - Introduction of foreign genetic material using vectors

C12N 005/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

A61K 039/395 Medicinal preparations containing antigens or antibodies - Antibodies

C07K 016/00 Immunoglobulins, e.g. monoclonal or polyclonal antibodies

Event Publications

14 October 2004 Complete Application Filed

21 October 2004 Application Open to Public Inspection

  Published as AU-A-2004216585

28 August 2008 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(e). Examination has been requested or an examination report has issued for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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