Spirocyclic compounds as HDAC inhibitors

Details for Australian Patent Application No. 2006318773 (hide)

Owner Merck Sharp & Dohme Corp.

Inventors Heidebrecht, Richard W.; Close, Joshua; Kattar, Solomon D.; Tempest, Paul; Mampreian, Dawn M.; Kliman, Laura T.; Miller, Thomas; Sloman, David L.; Zabierek, Anna A.; Berk, Scott C.; Stanton, Matthew G.; Hamblett, Christopher; Methot, Joey L.

Agent Spruson & Ferguson

Pub. Number AU-B-2006318773

PCT Pub. Number WO2007/061880

Priority 60/739,324 23.11.05 US

Filing date 17 November 2006

Wipo publication date 31 May 2007

Acceptance publication date 22 March 2012

International Classifications

C07D 471/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/407 (2006.01) - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 31/424 (2006.01) - condensed with heterocyclic ring systems, e.g. clavulanic acid

A61K 31/438 (2006.01) - the ring being spiro-condensed with carbocyclic or heterocyclic ring systems

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 35/00 (2006.01) Antineoplastic agents

C07D 487/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 491/10 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07D 498/10 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

Event Publications

5 June 2008 PCT application entered the National Phase

  PCT publication WO2007/061880 Priority application(s): WO2007/061880

28 January 2010 Alteration of Name

  The name of the applicant has been altered to Merck Sharp & Dohme Corp.

22 March 2012 Application Accepted

  Published as AU-B-2006318773

19 July 2012 Standard Patent Sealed

11 October 2012 Alteration of Name

  The name of the patentee has been altered to Merck Sharp & Dohme Corp.

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