Nitroaniline-based alkylating agents and their use as prodrugs

Details for Australian Patent Application No. 2003278628 (hide)

Owner Auckland UniServices Limited

Inventors Wilson, William Robert; Atwell, Graham J.; Patterson, Adam V.; Denny, William Alexander; Yang, Shangjin

Agent A J Park

Pub. Number AU-B-2003278628

PCT Number PCT/NZ03/00225

PCT Pub. Number WO2004/033415

Priority NZ 521851 08.10.02 NZ

Filing date 8 October 2003

Wipo publication date 4 May 2004

Acceptance publication date 23 September 2010

International Classifications

C07C 237/30 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

A61P 35/00 (2006.01) Antineoplastic agents

C07C 309/66 (2006.01) Sulfonic acids

C07C 311/39 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 263/04 (2006.01) Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 295/13 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 317/28 (2006.01) Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

Event Publications

26 February 2004 Complete Application Filed

  Priority application(s): NZ 521851 08.10.02 NZ

3 June 2004 Application Open to Public Inspection

  Published as AU-B-2003278628

19 October 2006 Amendment Made

  The nature of the amendment is:Add co-inventor Patterson, Adam V. 2004

23 September 2010 Application Accepted

  Published as AU-B-2003278628

20 January 2011 Standard Patent Sealed

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