Owner Mercian Corporation Eisai R&D Management Co., Ltd.

Inventors Fukud, Yoshio; Yoshida, Masashi; Nakashima, Takashi; Nagai, Mitsuo; Tsuchida, Toshio; Kanada, Regina Mikie; Kotake, Yoshihiko; Nijima, Jun

Agent Davies Collison Cave

Pub. Number AU-B-2003241927

PCT Number PCT/JP03/06779

PCT Pub. Number WO2003/099813

Priority 2003-63176 10.03.03 JP; 2002-155853 29.05.02 JP; 2002-223355 31.07.02 JP

Filing date 29 May 2003

Wipo publication date 12 December 2003

Acceptance publication date 18 June 2009

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

A61K 31/336 (2006.01) - having three-membered rings, e.g. oxirane, fumagillin

A61K 31/366 (2006.01) - having six-membered rings, e.g. delta-lactones

A61K 31/4025 (2006.01) - not condensed and containing further heterocyclic rings, e.g. cromakalim

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/4523 (2006.01) - containing further heterocyclic ring systems

A61K 31/454 (2006.01)

A61K 31/4545 (2006.01)

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/5377 (2006.01)

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 27/02 (2006.01) Drugs for disorders of the senses

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 35/00 (2006.01) Antineoplastic agents

A61P 35/02 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 407/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 407/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 487/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups