Owner Glaxo Group Limited

Inventors Looker, Brian Edgar; Procopiou, Panayiotis Alexandrou; Box, Philip Charles; Coe, Diane Mary

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002326026

PCT Number PCT/GB02/04140

PCT Pub. Number WO2003/024439

Priority 0126997.6 09.11.01 GB; 0122201.7 14.09.01 GB

Filing date 11 September 2002

Wipo publication date 1 April 2003

Acceptance publication date 28 April 2005

A61K 031/133 - having hydroxy groups, e.g. sphingosine

C07D 513/04 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C07C 271/38 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07D 239/54 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 333/38 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07C 233/75 Carboxylic acid amides

C07C 237/40 Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07C 275/40 Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07D 333/34 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07C 217/76 Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 317/22 Sulfones

C07C 325/02 Thioaldehydes

C07C 275/32 Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07C 217/08 Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 311/29 Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

A61P 011/06 Drugs for disorders of the respiratory system

C07C 317/14 Sulfones

C07C 311/08 Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 213/82 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07C 311/21 Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups