Owner Amgen Inc.

Inventors Bregman, Howard; Buchanan, John L.; Chakka, Nagasree; Dimauro, Erin F.; Du, Bingfan; Nguyen, Hanh Nho; Zheng, Xiao Mei

Agent Shelston IP

Pub. Number AU-A-2011218167

PCT Pub. Number WO2011/103196

Priority 61/305,235 17.02.10 US

Filing date 16 February 2011

Wipo publication date 25 August 2011

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/4427 - containing further heterocyclic ring systems

A61K 31/505 - Pyrimidines

A61K 31/506 - not condensed and containing further heterocyclic rings

A61K 31/53 - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 239/48 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 251/48 Heterocyclic compounds containing 1,3,5-triazine rings

C07D 401/04 Heterocyclic compounds containing two or more hetero rings

C07D 403/04 Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 471/10 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups