Substituted aminopropionic derivatives as neprilysin inhibitors

Details for Australian Patent Application No. 2010251967 (hide)

Owner Novartis AG

Inventors Coppola, Gary Mark; Iwaki, Yuki; Karki, Rajeshri Ganesh; Kawanami, Toshio; Ksander, Gary Michael; Mogi, Muneto; Sun, Robert

Agent Davies Collison Cave

Pub. Number AU-A-2010251967

PCT Pub. Number WO2010/136493

Priority 61/181,756 28.05.09 US; 61/263,145 20.11.09 US; 61/324,943 16.04.10 US

Filing date 26 May 2010

Wipo publication date 2 December 2010

International Classifications

C07D 213/82 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/21 (2006.01) - Esters, e.g. nitroglycerine, selenocyanates

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

C07C 233/47 (2006.01) Carboxylic acid amides

C07D 239/36 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 261/18 (2006.01) Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 271/06 (2006.01) Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms

Event Publications

8 December 2011 PCT application entered the National Phase

  PCT publication WO2010/136493 Priority application(s): WO2010/136493

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