Owner Vertex Pharmaceuticals Incorporated

Inventors Aronov, Alex; Come, Jon; Cottrell, Kevin; Grey, Ronald; Le Tiran, Amaud; Marone, Valerie; Martinez-Botella, Gabriel; Messersmith, David; Huck, Emilie Porter

Agent Baldwins

Pub. Number AU-A-2010250055

PCT Pub. Number WO2010/135014

Priority 61/156,139 27.02.09 US

Filing date 25 February 2010

Wipo publication date 25 November 2010

C07D 417/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/501 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 513/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or