Owner F. Hoffmann-La Roche AG

Inventors Lee, Eun Kyung; Schoenfeld, Ryan Craig; Talamas, Francisco Xavier

Agent Spruson & Ferguson

Pub. Number AU-A-2010240888

PCT Pub. Number WO2010/122082

Priority 61/172,723 25.04.09 US

Filing date 22 April 2010

Wipo publication date 28 October 2010

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/4412 (2006.01) - having oxo groups directly attached to the heterocyclic ring

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/50 (2006.01) - Pyridazines

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61P 31/14 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

C07D 213/76 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 237/14 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/54 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/18 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 405/04 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom