Owner F. Hoffmann-La Roche AG

Inventors Berthel, Steven Joseph; Firooznia, Fariborz; Fishlock, Daniel; Hong, Jun-Bae; Lou, Yan; Lucas, Matthew C.; Owens, Thimothy D.; Sarma, Keshab; Sweeney, Zachary Kevin; Taygerly, Joshua Paul Gergely

Agent Davies Collison Cave

Pub. Number AU-A-2010220435

PCT Pub. Number WO2010/100070

Priority 61/300,064 01.02.10 US; 61/209,021 02.03.09 US

Filing date 25 February 2010

Wipo publication date 10 September 2010

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/4412 (2006.01) - having oxo groups directly attached to the heterocyclic ring

A61K 31/444 (2006.01)

A61K 31/497 (2006.01)

A61K 31/501 (2006.01) - not condensed and containing further heterocyclic rings

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms