Means and methods for modulating NOTCH3 protein expression and/or the coding region of NOTCH3; compositions and use thereof in the treatment of cadasil

Details for Australian Patent Application No. 2010207073 (hide)

Owner Academisch Ziekenhuis Leiden h.o.d.n. LUMC

Inventors Lesnik Oberstein, Saskia Anne-Marie Jenny; Van Ommen, Garrit-Jan Boudewijn; Rus, Adriana Marie; Dauwerse, Johannes Gregorius

Agent Freehills

Pub. Number AU-A-2010207073

PCT Pub. Number WO2010/085151

Priority 09151326.7 26.01.09 EP

Filing date 26 January 2010

Wipo publication date 29 July 2010

International Classifications

C07K 14/705 (2006.01) Peptides having more than 20 amino acids

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

Event Publications

18 August 2011 PCT application entered the National Phase

  PCT publication WO2010/085151 Priority application(s): WO2010/085151

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