Owner Wisconsin Alumni Research Foundation Xenon Pharmaceuticals, Inc.

Inventors Attie, Alan D.; Brownlie, Alison J.; GrayKeller, Mark P.; Hayden, Michael R.; Miyazaki, Makoto; Ntambi, James M.

Agent Spruson & Ferguson

Pub. Number AU-B-2010200879

Parent 2007201711

Filing date 9 March 2010

Wipo publication date 1 April 2010

Acceptance publication date 19 January 2012

C07K 16/40 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against enzymes

A61K 31/00 (2006.01)

A61K 31/201 (2006.01)

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/4439 (2006.01)

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 3/06 (2006.01) Drugs for disorders of the metabolism

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/00 (2006.01) Enzymes, e.g. ligases (6.)

C12N 9/02 (2006.01) Enzymes, e.g. ligases (6.) - Oxidoreductases (1.), e.g. luciferase

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

C12N 15/113 (2010.01) Mutation or genetic engineering - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

C12Q 1/25 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving enzymes not classifiable in groups

C12Q 1/26 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving oxidoreductase

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations