Owner Isis Pharmaceuticals, Inc.

Inventors Graham, Mark J.; Crooke, Rosanne M.

Agent Pizzeys

Pub. Number AU-B-2010200325

Parent 2004256404

Filing date 28 January 2010

Wipo publication date 18 February 2010

Acceptance publication date 16 August 2012

A61K 48/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

C07H 21/02 Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/00 Mutation or genetic engineering

C12N 15/113 Mutation or genetic engineering - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

C12Q 1/68 Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids