Process and intermediates for the synthesis of 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl) - ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4. 5]decan-2-one compounds

Details for Australian Patent Application No. 2009289598 (hide)

Owner OPKO HEALTH, INC.

Inventors Wu, George G.; Werne, Gerald; Fu, Xiaoyong; Orr, Robert K.; Chen, Frank Xing; Cui, Jian; Sprague, Victoria M.; Zhang, Fucheng; Xie, Ji; Zeng, Liansheng; Castellanos, Louis Peter; Chen, Yuyin; Poirier, Marc; Mergelsberg, Ingrid

Agent Griffith Hack

Pub. Number AU-A-2009289598

PCT Pub. Number WO2010/028232

Priority 61/094,474 05.09.08 US

Filing date 4 September 2009

Wipo publication date 11 March 2010

International Classifications

C07D 207/26 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 471/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 498/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

Event Publications

31 March 2011 PCT application entered the National Phase

  PCT publication WO2010/028232 Priority application(s): WO2010/028232

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