Macrocyclics pyrimidines as Aurora kinase inhibitors

Details for Australian Patent Application No. 2009288021 (hide)

Owner MERCK PATENT GMBH

Inventors Yu, Henry; De Selm, Lizbeth Celeste; Jiang, Xuliang; Askew Jr., Benny C.; Karra, Srinivasa R.; Goutopoulos, Andreas

Agent Griffith Hack

Pub. Number AU-A-2009288021

PCT Pub. Number WO2010/028116

Priority 61/191,505 08.09.08 US

Filing date 3 September 2009

Wipo publication date 11 March 2010

International Classifications

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/529 (2006.01) - forming part of bridged ring systems

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 31/00 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

C07D 295/096 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 487/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 487/18 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 498/08 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 498/18 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 513/08 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C07D 513/18 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C07D 515/08 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

Event Publications

10 March 2011 PCT application entered the National Phase

  PCT publication WO2010/028116 Priority application(s): WO2010/028116

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