Owner F. Hoffmann-La Roche AG

Inventors Roche, Olivier; Maerki, Hans P.; Mattei, Patrizio; Green, Luke; Binggeli, Alfred; Ricklin, Fabienne; Hartmann, Guido; Aebi, Johannes

Agent Spruson & Ferguson

Pub. Number AU-A-2009272893

PCT Pub. Number WO2010/006938

Priority 08160534.7 16.07.08 EP

Filing date 6 July 2009

Wipo publication date 21 January 2010

C07D 241/08 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/497 (2006.01)

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

C07D 243/08 (2006.01) Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

C07D 285/36 (2006.01) Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom