Selective hydroxamic acid based MMP12 and MMP-13 inhibitors

Details for Australian Patent Application No. 2009272807 (hide)

Owner Novartis AG

Inventors Shultz, Michael; Tommasi, Ruben Alberto; Weiler, Sven; McQuire, Leslie Wighton; Rogel, Olivier

Agent Davies Collison Cave

Pub. Number AU-B-2009272807

PCT Pub. Number WO2010/007027

Priority 61/080,472 14.07.08 US

Filing date 13 July 2009

Wipo publication date 21 January 2010

Acceptance publication date 24 May 2012

International Classifications

C07C 311/19 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

A61K 31/18 (2006.01) - Sulfonamides

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 35/00 (2006.01) Antineoplastic agents

C07C 311/29 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 311/44 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 207/48 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 211/96 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/53 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/36 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 223/06 (2006.01) Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom

C07D 277/06 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 277/80 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 309/06 (2006.01) Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings

Event Publications

27 January 2011 PCT application entered the National Phase

  PCT publication WO2010/007027 Priority application(s): WO2010/007027

24 May 2012 Application Accepted

  Published as AU-B-2009272807

20 September 2012 Standard Patent Sealed

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