Processes and compounds for the preparation of normorphinans

Details for Australian Patent Application No. 2009251427 (hide)

Owner Mallinckrodt Inc.

Inventors Halvachs, Robert E.; Grote, Christopher W.; Cantrell, Gary L.; Wang, Peter X.; Moser, Frank W.; Jiang, Tao

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2009251427

PCT Pub. Number WO2009/146288

Priority 61/056,079 27.05.08 US

Filing date 21 May 2009

Wipo publication date 3 December 2009

International Classifications

C07D 221/28 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

A61K 31/485 (2006.01) - Morphinan derivatives, e.g. morphine, codeine

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 489/02 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

C07D 489/08 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Event Publications

16 December 2010 PCT application entered the National Phase

  PCT publication WO2009/146288 Priority application(s): WO2009/146288

3 November 2011 Assignment before Grant

  Mallinckrodt Inc. The application has been assigned to Mallinckrodt LLC

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