Owner F. Hoffmann-La Roche AG

Inventors Sarabu, Ramakanth; Berthel, Steven Joseph; Brinkman, John A.; Qian, Yimin; Hayden, Stuart; Kester, Robert Francis; Tilley, Jefferson Wright; McDermott, Lee Apostle; Haynes, Nancy-Ellen; Scott, Nathan Robert

Agent Spruson & Ferguson

Pub. Number AU-A-2009237794

PCT Pub. Number WO2009/127546

Priority 61/145,761 20.01.09 US; 61/045,370 16.04.08 US

Filing date 6 April 2009

Wipo publication date 22 October 2009

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/4155 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/427 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/497 (2006.01)

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07F 7/18 (2006.01) Compounds containing elements of the 4th Group of the Periodic System