Small molecule inhibitors of the pleckstrin homology domain and methods for using same

Details for Australian Patent Application No. 2009236256 (hide)

Owner Arizona Board of Regents on behalf of the University of Arizona The Board of Regents of the University of Texas System

Inventors Zhang, Shuxing; Powis, Garth; Meuillet, Emmanuelle J.; Mash, Eugene A.; Mahadevan, Daruka; Gohkale, Vijay M.

Agent Pizzeys

Pub. Number AU-A-2009236256

PCT Pub. Number WO2009/129267

Priority 61/124,053 14.04.08 US; 61/199,497 17.11.08 US

Filing date 14 April 2009

Wipo publication date 22 October 2009

International Classifications

C07C 233/80 (2006.01) Carboxylic acid amides

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 237/18 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/69 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 263/40 (2006.01) Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 271/10 (2006.01) Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms

C07D 285/12 (2006.01) Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 333/36 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07F 9/44 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

C07F 9/74 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

Event Publications

4 November 2010 PCT application entered the National Phase

  PCT publication WO2009/129267 Priority application(s): WO2009/129267

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