Owner Janssen Pharmaceutica NV

Inventors Gomez, Laurent; Wiener, John, J.M.; Sappey, Kathleen C.; Chrovian, Christa C.; Bacani, Genesis M.; Santillan Jr., Alejandro; Grice, Cheryl A.; LandryBayle, Adrienne M.; Broggini, Diego; Cheung, Eugene Y.; Mani, Neelakandha S.; Deng, Xiaohu; Wickboldt, Alvah T.; Lochner, Susanne; Sepassi, Kia; Zinser, Hartmut; Liang, Jimmy T.; Lee-Dutra, Alice; Fourine, Anne M.; Tanis, Virginia M.; Kearney, Aaron M.

Agent Shelston IP

Pub. Number AU-A-2009234140

PCT Pub. Number WO2009/126806

Priority 61/149,129 02.02.09 US; 61/044,349 11.04.08 US

Filing date 9 April 2009

Wipo publication date 15 October 2009

C07D 453/02 (2006.01) Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids

A61K 31/437 (2006.01)

A61K 31/4985 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/5377 (2006.01)

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 498/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 513/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C12N 9/50 (2006.01) Enzymes, e.g. ligases (6.) - Proteinases