Owner Vertex Pharmaceuticals Incorporated

Inventors Perni, Robert B.; Pitlik, Janos; Cottrell, Kevin M.; Courtney, Lawrence F.; Farmer, Luc J.; Murcko, Mark A.; Van Drie, John H.

Agent Cullens

Pub. Number AU-A-2009233604

Parent 2003223602

Filing date 30 October 2009

Wipo publication date 26 November 2009

C12N 9/99 (2006.01) Enzymes, e.g. ligases (6.) - Enzyme inactivation by chemical treatment

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 38/04 (2006.01) Medicinal preparations containing peptides - Peptides having up to 20 amino acids in a fully defined sequence

A61P 1/16 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 31/12 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/14 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 37/02 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 209/42 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07K 5/04 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 5/06 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 5/10 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 7/02 (2006.01) Peptides having 5 to 20 amino acids in a fully defined sequence