Owner Vertex Pharmaceuticals Incorporated

Inventors Bear, Brian; Miller, Mark; Hadida-Ruah, Sara; Grootenhuis, Peter; Zhou, Jinglan

Agent Baldwins

Pub. Number AU-A-2009231993

PCT Pub. Number WO2009/123896

Priority 61/040,776 31.03.08 US

Filing date 25 March 2009

Wipo publication date 8 October 2009

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms