Owner Novartis AG

Inventors Poon, Daniel; Smith, Aaron; AntoniosMcCrea, William R.; Zhang, Qiong; McKenna, Maureen; Renhowe, Paul A.; Machajewski, Timothy D.; Shafer, Cynthia M.; Huang, Zilin; Xu, Yongjin; Jin, Jeff; Sendzik, Martin

Agent Davies Collison Cave

Pub. Number AU-A-2009227013

PCT Pub. Number WO2009/115572

Priority 61/038,723 21.03.08 US; 61/208,458 24.02.09 US

Filing date 19 March 2009

Wipo publication date 24 September 2009

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/444 (2006.01)

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 35/00 (2006.01) Antineoplastic agents

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 498/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms