1-benzyl-3-hydr0xymethylindaz0le derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, and CX3CR1

Details for Australian Patent Application No. 2009221063 (hide)

Owner Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.

Inventors Cazzolla, Nicola; Guglielmotti, Angelo; Mangano, Giorgina; Furlotti, Guido

Agent Griffith Hack

Pub. Number AU-A-2009221063

PCT Pub. Number WO2009/109654

Priority 08425141.2 07.03.08 EP

Filing date 6 March 2009

Wipo publication date 11 September 2009

International Classifications

C07D 231/54 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

A61K 31/416 (2006.01) - condensed with carbocyclic ring systems, e.g. indazole

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 13/00 (2006.01) Drugs for disorders of the urinary system

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

Event Publications

9 September 2010 PCT application entered the National Phase

  PCT publication WO2009/109654 Priority application(s): WO2009/109654

1 March 2012 Amendment Made

  The nature of the amendment is: Amend the invention title to read 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, and CX3CR1

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