New process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5trien-7-yl)nitrile and application in the synthesis of Ivabradine

Details for Australian Patent Application No. 2009208068 (hide)

Owner Les Laboratoires Servier

Inventors Lecouve, Jean-Pierre; Phan, Maryse; Gojon, Eric; Lerestif, Jean-Michel; Dron, Daniel

Agent Allens Arthur Robinson

Pub. Number AU-A-2009208068

Priority 08/04755 29.08.08 FR

Filing date 7 August 2009

Wipo publication date 18 March 2010

International Classifications

C07B 57/00 (2006.01) Separation of optically-active compounds

C07C 217/74 (2006.01) Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 255/47 (2006.01) Carboxylic acid nitriles

C07C 271/16 (2006.01) Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07D 223/16 (2006.01) Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom

Event Publications

27 August 2009 Complete Application Filed

  Priority application(s): 08/04755 29.08.08 FR

24 September 2009 Corrigenda

  Complete Applications Filed - Name Index Under the name Les laboratories Servier, Application No. 2009208068,under INID (54) correct the title to read New process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl)nitrile and application in the synthesis of Ivabradine.

18 March 2010 Application Open to Public Inspection

  Published as AU-A-2009208068

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