Owner Medarex, Inc.

Inventors Halk, Edward L.; Korman, Alan J.; Deo, Yashwant M.; Lonberg, Nils; Keler, Tibor P.

Agent Spruson & Ferguson

Pub. Number AU-B-2009202447

Parent 2006201520

Filing date 18 June 2009

Wipo publication date 9 July 2009

Acceptance publication date 24 November 2011

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

A01K 67/027 (2006.01) Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/10 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/12 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/02 (2006.01) Drugs for immunological or allergic disorders

C07K 16/28 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 19/00 (2006.01) Hybrid peptides

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/02 (2006.01) Mutation or genetic engineering - Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12N 15/85 (2006.01) Mutation or genetic engineering - for animal cells