Substituted 4H-chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof

Details for Australian Patent Application No. 2009200374 (hide)

Owner Cytovia, Inc.

Inventors Jiang, Songchun; Cai, Xiong Sui; Storer, Richard; Zhang, Hong

Agent Houlihan2

Pub. Number AU-B-2009200374

Parent 2002314781

Filing date 3 February 2009

Wipo publication date 26 March 2009

Acceptance publication date 27 October 2011

International Classifications

C07D 311/58 (2006.01) Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings

A61K 31/35 (2006.01) - having six-membered rings with one oxygen as the only ring hetero atom

A61K 31/352 (2006.01) - condensed with carbocyclic rings, e.g. cannabinols, methantheline

A61K 31/38 (2006.01) - having sulfur as a ring hetero atom

A61K 31/382 (2006.01) - having six-membered rings, e.g. thioxanthenes

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/4025 (2006.01) - not condensed and containing further heterocyclic rings, e.g. cromakalim

A61K 31/404 (2006.01)

A61K 31/407 (2006.01) - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 31/415 (2006.01) - 1,2-Diazoles

A61K 31/4188 (2006.01)

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/453 (2006.01)

A61K 31/47 (2006.01) - Quinolines

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/497 (2006.01)

A61K 31/4985 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems

A61K 31/50 (2006.01) - Pyridazines

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/535 (2006.01) - having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

A61K 31/5377

Event Publications

19 February 2009 Complete Application Filed

26 March 2009 Application Open to Public Inspection

  Published as AU-B-2009200374

9 December 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(d). Examination has been requested or an examination report has issued for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

2 June 2011 Section 223 Application Received

  Cytovia, Inc. An application to extend the time from 16 May 2010 to 16 Mar 2011 in which to pay a continuation fee has been filed . Address for service in Australia - Houlihan2 Level 1 70 Doncaster Road Balwyn North VIC 3104 2010

21 July 2011 Section 223 Application Allowed

  Cytovia, Inc. The time in which to pay a continuation fee has been extended to 16 Mar 2011. Address for service in Australia - Houlihan2 Level 1 70 Doncaster Road Balwyn North VIC 3104 Extensions of Time, Section 223

27 October 2011 Application Accepted

  Published as AU-B-2009200374

23 February 2012 Standard Patent Sealed

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