Owner Amgen Inc.

Inventors Dai, Kang; Mihalic, Jeffrey; McGee, Lawrence R.; Wang, Xiaodong; Li, Zhihong; Eksterowicz, John; Deignan, Jeffrey; Fisher, Benjamin; Connors, Richard V.; Sharma, Rajiv; Fan, Pingchen; Fu, Jiasheng; McMinn, Dustin; Li, Kexue

Agent Shelston IP

Pub. Number AU-A-2008343932

PCT Pub. Number WO2009/085185

Priority 61/008,429 19.12.07 US

Filing date 18 December 2008

Wipo publication date 9 July 2009

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61P 35/00 (2006.01) Antineoplastic agents

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 487/14 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 498/10 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 513/14 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or