Silencing of polo-like kinase expression using interfering RNA

Details for Australian Patent Application No. 2008342535 (hide)

Owner Protiva Biotherapeutics, Inc.

Inventors MacLachlan, Ian; Judge, Adam

Agent Davies Collison Cave

Pub. Number AU-A-2008342535

PCT Pub. Number WO2009/082817

Priority 61/100,653 26.09.08 US; 61/017,075 27.12.07 US; 61/045,228 15.04.08 US

Filing date 23 December 2008

Wipo publication date 9 July 2009

International Classifications

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

A61K 9/00 (2006.01) Medicinal preparations characterised by special physical form

A61K 31/7105 (2006.01) - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links

A61K 31/712 (2006.01) - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose

A61K 31/713 (2006.01) - Double-stranded nucleic acids or oligonucleotides

A61K 47/24 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen or sulfur

A61K 47/28 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Steroids

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 35/00 (2006.01) Antineoplastic agents

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 9/12 (2006.01) Enzymes, e.g. ligases (6.) - transferring phosphorus containing groups, e.g. kinases (2.7)

C12N 15/10 (2006.01) Mutation or genetic engineering - Processes for the isolation, preparation or purification of DNA or RNA

C12N 15/54 (2006.01) Mutation or genetic engineering - Transferases (2)

C12N 15/87 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

C12N 15/88 (2006.01) Mutation or genetic engineering

Event Publications

29 July 2010 PCT application entered the National Phase

  PCT publication WO2009/082817 Priority application(s): WO2009/082817

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