Owner AstraZeneca AB

Inventors Sohn, Daniel; Ek, Maria E.; Bylund, Johan; Gravenfors, Ylva; Holenz, Jorg; Nordvall, Gunnar; Von Berg, Stefan; Viklund, Jenny; Vallin, Karl S.A.; Minidis, Alexander

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2008341173

PCT Pub. Number WO2009/082347

Priority 61/015,287 20.12.07 US

Filing date 18 December 2008

Wipo publication date 2 July 2009

Acceptance publication date 15 December 2011

C07D 307/79 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

A61K 31/18 (2006.01) - Sulfonamides

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/404 (2006.01)

A61K 31/4155 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/4245 (2006.01) - Oxadiazoles

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 31/4418 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61K 31/505 (2006.01) - Pyrimidines

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07C 311/44 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 209/10 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/30 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 233/96 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 271/10 (2006.01) Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms

C07D 277/32 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 307/10 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 307/38 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/34 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom