Indazolyl, benzimidazolyl, benzotriazolyl substituted indolinone derivatives as kinase inhibitors useful in the treatment of cancer

Details for Australian Patent Application No. 2008340991 (hide)

Owner University Health Network

Inventors Pan, Guohua; Forrest, Bryan T.; Laufer, Radoslaw; Feher, Miklos; Pauls, Heinz W.; Sampson, Peter Brent; Li, Sze-Wan; Liu, Yong

Agent Davies Collison Cave

Pub. Number AU-B-2008340991

PCT Pub. Number WO2009/079767

Priority 61/008,865 21.12.07 US; 61/131,717 11.06.08 US

Filing date 19 December 2008

Wipo publication date 2 July 2009

Acceptance publication date 23 February 2012

International Classifications

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/416 (2006.01) - condensed with carbocyclic ring systems, e.g. indazole

A61K 31/4192 (2006.01) - 1,2,3-Triazoles

A61P 35/00 (2006.01) Antineoplastic agents

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D 513/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

Event Publications

15 July 2010 PCT application entered the National Phase

  PCT publication WO2009/079767 Priority application(s): WO2009/079767

23 February 2012 Application Accepted

  Published as AU-B-2008340991

21 June 2012 Standard Patent Sealed

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