Owner SCHERING CORPORATION

Inventors Lankin, Claire M.; Dai, Xing; Xia, Yan; Jayne, Charles Lee; Boyle, Craig D.; Neelamkavil, Santhosh Francis; Harris, Joel M.; Liu, Hong; Shah, Unmesh G.; Chackalamannil, Samuel; Stamford, Andrew W.; Neustadt, Bernard R.; Greenlee, William J.

Agent Griffith Hack

Pub. Number AU-A-2008317057

PCT Pub. Number WO2009/055331

Priority 60/981,677 22.10.07 US

Filing date 20 October 2008

Wipo publication date 30 April 2009

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/439 (2006.01) - the ring forming part of a bridged ring system, e.g. quinuclidine

A61K 31/46 (2006.01) - 8-Azabicyclo [3.2.1] octane

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/537 (2006.01) - spiro-condensed or forming part of bridged ring systems

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

C07D 451/06 (2006.01) Heterocyclic compounds containing condensed hetero ring systems

C07D 471/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 491/08 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07D 495/08 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D 498/08 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms