Owner Janssen Pharmaceutica, N.V.

Inventors Ho, Chih Yung

Agent Shelston IP

Pub. Number AU-A-2008312355

PCT Pub. Number WO2009/052334

Priority 60/981,209 19.10.07 US

Filing date 17 October 2008

Wipo publication date 23 April 2009

C07C 57/42 (2006.01) Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms

A61K 31/192 (2006.01)

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07C 57/58 (2006.01) Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms

C07C 57/60 (2006.01) Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms

C07C 59/56 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 59/88 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 255/57 (2006.01) Carboxylic acid nitriles

C07D 213/61 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members