Owner Vertex Pharmaceuticals Incorporated

Inventors Wilson, Dean; Joshi, Pramod; Krenitsky, Paul; Termin, Andreas

Agent Baldwins

Pub. Number AU-A-2008310660

PCT Pub. Number WO2009/049180

Priority 60/979,258 11.10.07 US

Filing date 10 October 2008

Wipo publication date 16 April 2009

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 213/82 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 249/10 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 261/18 (2006.01) Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 263/34 (2006.01) Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 277/56 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 285/12 (2006.01) Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 307/68 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/38 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom