Owner F. Hoffmann-La Roche AG

Inventors Zhao, Chunlin; Chu, Xin-Jie; Vu, Binh Thanh; Bartkovitz, David Joseph; Lovey, Allen John; Li, Hongju; Cai, Jianping

Agent Davies Collison Cave

Pub. Number AU-A-2008309759

PCT Pub. Number WO2009/047161

Priority 61/092,759 29.08.08 US; 60/978,506 09.10.07 US

Filing date 30 September 2008

Wipo publication date 16 April 2009

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/454 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group