Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides

Details for Australian Patent Application No. 2008307510 (hide)

Owner Onyx Therapeutics, Inc.

Inventors Laidig, Guy J.; Phiasivongsa, Pasit; Fuller, William Dean; Sehl, Louis C.

Agent Shelston IP

Pub. Number AU-A-2008307510

PCT Pub. Number WO2009/045497

Priority 61/008,987 20.12.07 US; 60/997,613 04.10.07 US

Filing date 3 October 2008

Wipo publication date 9 April 2009

International Classifications

C07K 5/10 (2006.01) Peptides having up to four amino acids in a fully defined sequence

A61P 19/08 (2006.01) Drugs for skeletal disorders

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 31/00 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 33/00 (2006.01) Antiparasitic agents

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

C07D 303/36 (2006.01) Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom

C07K 5/107 (2006.01) Peptides having up to four amino acids in a fully defined sequence

Event Publications

20 May 2010 PCT application entered the National Phase

  PCT publication WO2009/045497 Priority application(s): WO2009/045497

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