Owner F. Hoffmann-La Roche AG

Inventors Mattei, Patrizio; Maerki, Hans P.; Hartmann, Guido; Green, Luke; Ricklin, Fabienne; Aebi, Johannes; Roche, Olivier; Binggeli, Alfred

Agent Spruson & Ferguson

Pub. Number AU-A-2008307158

PCT Pub. Number WO2009/043747

Priority 07117656.4 01.10.07 EP

Filing date 22 September 2008

Wipo publication date 9 April 2009

A61K 31/454 (2006.01)

A61K 31/4545 (2006.01)

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 211/58 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 243/08 (2006.01) Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms