Owner Portola Pharmaceuticals, Inc.

Inventors Phillips, David R.; Andre, Patrick; Sinha, Uma; Lu, Genmin

Agent Freehills

Pub. Number AU-A-2008304192

PCT Pub. Number WO2009/042962

Priority 61/090,574 20.08.08 US; 60/976,343 28.09.07 US

Filing date 26 September 2008

Wipo publication date 2 April 2009

A61P 7/02 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61K 31/4545 (2006.01)

A61K 31/5377 (2006.01)

A61K 31/715 (2006.01) - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages

A61K 31/727 (2006.01)

A61K 38/36 (2006.01) Medicinal preparations containing peptides - Blood coagulation or fibrinolysis factors

A61K 38/48 (2006.01) Medicinal preparations containing peptides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 7/04 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07K 14/00 (2006.01) Peptides having more than 20 amino acids

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/64 (2006.01) Enzymes, e.g. ligases (6.) - derived from animal tissue, e.g. rennin

C12P 21/00 (2006.01) Preparation of peptides or proteins