Owner IRM LLC

Inventors Epple, Robert; Nikulin, Victor; Azimioara, Mihai; Cow, Christopher; Michellys, Pierre-yves; Mutnick, Daniel; Lelais, Gerald; Alper, Phillip; Jiang, Songchun; Westcott-Baker, Lucas

Agent Davies Collison Cave

Pub. Number AU-B-2008302570

PCT Pub. Number WO2009/038974

Priority 61/045,263 15.04.08 US; 60/974,064 20.09.07 US

Filing date 3 September 2008

Wipo publication date 26 March 2009

Acceptance publication date 31 May 2012

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 413/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 491/048 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or