Owner AstraZeneca AB

Inventors Dakin, Leslie; Janetka, James; Zheng, Xiaolan; Hird, Alexander; Su, Qibin; Yang, Bin; Russell, Daniel John; Fauber, Benjamin

Agent Davies Collison Cave

Pub. Number AU-A-2008291921

PCT Pub. Number WO2009/027746

Priority 61/036,658 14.03.08 US; 60/969,364 31.08.07 US

Filing date 29 August 2008

Wipo publication date 5 March 2009

C07D 213/30 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61P 35/00 (2006.01) Antineoplastic agents

C07D 213/40 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/73 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 233/61 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 473/00 (2006.01) Heterocyclic compounds containing purine ring systems

C07D 513/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or