Benzimidazole derivatives used as FXR agonists

Details for Australian Patent Application No. 2008291148 (hide)

Owner F. Hoffmann-La Roche AG

Inventors Martin, Rainer E.; Plancher, Jean-Marc; Richter, Hans; Taylor, Sven; Grether, Uwe; Bleicher, Konrad; Benson, Gregory Martin; Yang, Minmin

Agent Spruson & Ferguson

Pub. Number AU-B-2008291148

PCT Pub. Number WO2009/027264

Priority 07115005.6 27.08.07 EP

Filing date 19 August 2008

Wipo publication date 5 March 2009

Acceptance publication date 17 March 2011

International Classifications

C07D 235/12 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings

A61K 31/4184 (2006.01)

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

A61P 1/16 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 19/00 (2006.01) Drugs for skeletal disorders

A61P 25/16 (2006.01) Drugs for disorders of the nervous system

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

Event Publications

18 March 2010 PCT application entered the National Phase

  PCT publication WO2009/027264 Priority application(s): WO2009/027264

17 March 2011 Application Accepted

  Published as AU-B-2008291148

14 July 2011 Standard Patent Sealed

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