Optimized DNA and protein sequence of an antibody to improve quality and yield of bacterially expressed antibody fusion proteins

Details for Australian Patent Application No. 2008277936 (hide)

Owner TopoTarget Germany AG

Inventors Schwarz, Sylvia E.; Dalken, Benjamin; Wels, Winfried S.

Agent Davies Collison Cave

Pub. Number AU-A-2008277936

PCT Pub. Number WO2009/010228

Priority 07013750.0 13.07.07 EP; 60/949,580 13.07.07 US

Filing date 10 July 2008

Wipo publication date 22 January 2009

International Classifications

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 16/32 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 15/62 (2006.01) Mutation or genetic engineering - DNA sequences coding for fusion proteins

Event Publications

28 January 2010 PCT application entered the National Phase

  PCT publication WO2009/010228 Priority application(s): WO2009/010228

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