Owner Provid Pharmaceuticals, Inc. The United States of America as represented by the Department of Health and Human Services, NIH

Inventors Zhang, Guangtao; Cook, Charles M.; Kondapaka, Sudhir; Colasanti, Andrew; Waugh, David; Currens, Michael; Shoemaker, Robert; Jobson, Andy; Cardellina, John; Scudiero, Dominic; Pommier, Yves; Lountos, George; Self, Christopher R.

Agent Cullens

Pub. Number AU-A-2008267081

PCT Pub. Number WO2008/156573

Priority 60/934,375 12.06.07 US; 61/066,696 21.02.08 US

Filing date 9 June 2008

Wipo publication date 24 December 2008

C07D 209/42 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

A61K 31/34 (2006.01) - having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide

C07D 209/60 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/86 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 217/26 (2006.01) Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 231/56 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 233/52 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 277/50 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 277/82 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 307/68 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 307/85 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups