Owner Amgen Inc.

Inventors Kreiman, Charles; Zhong, Wenge; Croghan, Michael; Horne, Daniel; Kaller, Matthew; Dineen, Thomas; Xue, Qiufen; Patel, Vinod F.; Monenschein, Holger; Pennington, Lewis; Nguyen, Thomas; Hitchcock, Stephen; Yang, Bryant; Lopez, Patricia

Agent Shelston IP

Pub. Number AU-B-2008257145

PCT Pub. Number WO2008/147544

Priority 60/931,824 25.05.07 US

Filing date 23 May 2008

Wipo publication date 4 December 2008

Acceptance publication date 10 November 2011

C07D 221/06 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

A61K 31/438 (2006.01) - the ring being spiro-condensed with carbocyclic or heterocyclic ring systems

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07D 311/96 (2006.01) Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings

C07D 471/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 491/10 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07D 493/10 (2006.01) Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system

C07D 495/10 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms